tag:blogger.com,1999:blog-5977689274110133568.post2193996325446300455..comments2016-04-29T12:11:19.636-04:00Comments on The Daily Lipid: My New Wise Traditions Article on Nonalcoholic Fatty Liver DiseaseChris Masterjohnhttp://www.blogger.com/profile/09922003080748568167noreply@blogger.comBlogger15125tag:blogger.com,1999:blog-5977689274110133568.post-31395658663887981042012-06-16T12:07:06.574-04:002012-06-16T12:07:06.574-04:00Sorry, no I don&#39;t think it necessarily follows...Sorry, no I don&#39;t think it necessarily follows that *only* choline is important. However, I think that excess alcohol is much more likely to be harmful than excess fructose because it promotes oxidative stress. Animal studies suggest that low-PUFA, highly saturated fats are very powerfully protective against the effect of ethanol, though it hasn&#39;t been studied in humans to my knowledge.<br /><br />ChrisChris Masterjohnhttp://www.blogger.com/profile/09922003080748568167noreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-38646603998782532102012-06-16T12:02:19.411-04:002012-06-16T12:02:19.411-04:00did you ever get an answer?did you ever get an answer?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-74144767903329992902012-01-07T14:48:02.238-05:002012-01-07T14:48:02.238-05:00An interesting view, I think this sort of informat...An interesting view, I think this sort of information needs to be made more publicly available for people to fully understand the harm they are doing to their bodiesEmporia Lingeriehttp://www.emporialingerie.co.uk/noreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-84118664440683937822011-12-29T04:03:46.194-05:002011-12-29T04:03:46.194-05:00Thank you for the time and effort you put into you...Thank you for the time and effort you put into your blog posts, articles and your website. Informative stuff.hair losshttp://www.stophairlossnow.co.uknoreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-90086842062996270482011-06-12T17:34:48.308-04:002011-06-12T17:34:48.308-04:00A couple of things strike me: 1. If a diet suffic...A couple of things strike me:<br /><br />1. If a diet sufficiently rich in choline completely protects against fat accumulation in the liver due to fructose, ethanol or fat, does that mean that provided we have sufficient choline in our diet, we can guzzle on fructose to our heart&#39;s content? Ditto alcohol...?<br /><br /><br />2. Those of us on low carb (high fat) diets, even though we may abstain from fructose and alcohol, because we are high in dietary fat, also need to keep up our supply of choline (so lots of eggs and liver).montmorencyhttp://www.blogger.com/profile/12879422255762834319noreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-28185051356977492612011-04-21T10:30:59.709-04:002011-04-21T10:30:59.709-04:00I also meant to ask if there were other foods and ...I also meant to ask if there were other foods and drinks that &quot;use up&quot; folate (it appears that alcohol and smoking does)? It may be possible to reduce the folate requirement by eliminating any non-essentials that do.Frostynoreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-59575796944707624402011-04-21T10:15:41.590-04:002011-04-21T10:15:41.590-04:00Chris, I have been following your liver posts with...Chris, I have been following your liver posts with great interest. Thank you for the series.<br /><br />I have recently been researching aspartame in an attempt to cut through the BS that is rampant on the internet. I came across some posts by a doctor that mentioned that one of the by-products of the breakdown of aspartame, methanol, breaks down into formic acid, which is then metabolized by folate (fruit and vegetable juices also breakdown into higher concentrations of methanol but natively contain some folate). He also claims that caffeine requires folate to metabolize.<br /><br />&quot;But worse, in this case that added ‘cargo’ could well involve both folate issues and the caffeine in diet Pepsi. Caffeine generates two equivalents of formate during degradation compared to one from aspartame’s methanol. But both caffeine and aspartame require folate for detoxification, so again any issue with ‘diet Pepsi’ likely reflects personal health problems with folate or folate-related biochemistry, not the soft drink itself.&quot;<br /><br />http://whatdoesthesciencesay.wordpress.com/2010/06/13/aspartame-and-formaldehyde/<br /><br />This caught my attention, based on your recent blog posts on the liver, since folate is mentioned as preserving choline.<br /><br />I have tried to research these claims and, to my untrained eye, they appear valid. However, I am not a scientist and there is a lot of bad science out there to wade through so it is hard for me to tell if aspartame and caffeine &quot;use up&quot; folate in the body and can lead to a deficiency.<br /><br />In your research, have you run across anything that can back up these claims? Can consuming food and drinks containing caffeine and/or aspartame lead to folate deficiency, thus impacting the liver negatively?Frostynoreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-18740405795265375512011-04-12T15:45:41.952-04:002011-04-12T15:45:41.952-04:00Is Wise Traditions only available in northern Amer...Is Wise Traditions only available in northern America?Timnoreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-266337530165329932011-04-11T02:00:06.582-04:002011-04-11T02:00:06.582-04:00I&#39;m kind of proud to myself that since the yea...I&#39;m kind of proud to myself that since the year started, I&#39;ve never been into any alcoholic stuff anymore. I just feel the need of having a clean living, having a sound mind as well as fit body. I find those things very lovely.thinning hairhttp://www.leimo.co.uk/noreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-35826090496033901102011-04-11T00:52:12.342-04:002011-04-11T00:52:12.342-04:00For anyone who has not seen this video, it describ...For anyone who has not seen this video, it describes in detail connections between fructose, alcohol, and fatty liver.<br /><br />http://www.youtube.com/watch?v=dBnniua6-oMAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-85193366030677301902011-04-08T03:20:48.321-04:002011-04-08T03:20:48.321-04:00Chris, Your blog rocks. Sorry my tweet seemed to d...Chris,<br />Your blog rocks. Sorry my tweet seemed to dismiss your reasoning here.<br /><br />@John, it&#39;s not about the calories. I&#39;m a 200lb lean, muscular guy who used to weigh 300lbs. I don&#39;t have to exercise anymore and haven&#39;t in 18 months. For 5 years time, I&#39;ve been on 5,000 calories/day, 60% fat, 20% protein, 20% veg (gf butter, beef &amp; lamb, egg yolks, coconut, MCT, avocado) diet. I am about to publish (Wiley &amp; Sons) my book about using this diet before and during preganancy to cause epigenetic changes to make smarter babies. www.betterbabybook.com<br /><br />Chris, I also researched extensively the role of endotoxins and exotoxins and came up with similar conclusions to yours, along with a map of low-toxin food choices, including cooking method changes. But the worst offender by far is not bacteria in the gut. It&#39;s low grade systemic yeast infections and exogenous low level mold in food. Both of these represent hormone disruption (estrogen mimicking) but even worse, they disrupt gut bacteria, making them excrete more toxins. <br /><br />In choline-sufficient diets, methionine may even be unhealthy. I have a paper floating around here somewhere looking at how restricting methionine, cysteine, and tryptophan caused dramatic reduction of aging on par with caloric restriction.<br /><br />Finally, while phosphatidyl choline is great, I reached a point where my acetylcholine levels got too high from using choline supplements (non-gmo soy lecithin, or alpha-GPC, CDP-choline, etc.) Egg yolks don&#39;t do this. The first symptom of acetylcholine excess was jaw clenching.<br /><br />Chris - like I said, you rock. If you ever want to present at www.smartlifeforum.org, just ask. Gary Taubes did recently. My hat goes off to you guys for doing the hard work to document and justify what I *know* works through my own experience as a biohacker.Dave Asprey (@bulletproofexec)http://www.bulletproofexecutive.comnoreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-28084400393451089602011-04-07T15:59:28.121-04:002011-04-07T15:59:28.121-04:00Hi Chris, Thank you for all the time and effort y...Hi Chris,<br /><br />Thank you for all the time and effort you put into your blog posts, articles and your website. I think you are a great educator, and for a layman like myself your work is a fantastic resource. I gain valuable new insights with every visit.<br /><br />This NAFLD article was almost like you read my mind. Ever since I commented in the fasting insulin/calories in-out post at Peter&#39;s Hyperlipid, I tried to come up with an explanation for weight gain/obesity due to overfeeding, without &#39;violating&#39; the leptin based lipostat theory. My best guess: liver impairment due to a choline deficiency, based on your &quot;Sweet Truth About Liver and Egg Yolks&quot; post (energy intake ↑ → choline requirement ↑). Sure enough, a few days later, your NAFLD article went online :-)<br /><br />The choline/nutrient deficiency hypothesis seems to have the potential to tie a lot of ends together: why things like refining, high palatability, chronic overeating, all can result in metabolic problems and secondary effects like weight gain.<br />And what&#39;s funny: on the surface conventional wisdom appears to be right about weight, in that it&#39;s all about calories. But reality seems more nuanced: it seems all about how many nutrients (and toxins) come with the calories.<br /><br /><br />JohnJohnhttp://www.blogger.com/profile/03386692711267693179noreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-79957190921410424142011-04-07T15:36:02.726-04:002011-04-07T15:36:02.726-04:00Thanks for this excelent article on Wise Tradition...Thanks for this excelent article on Wise Traditions. Are you aware of the study &quot;Dietary composition and nonalcoholic fatty liver disease&quot; that found a relative risk for inflammation of 6.5 with a higher CHO intake?<br />http://www.healthy.co.nz/news/154-low-fat-high-carb-diet-for-morbidly-obese-tied-to-liver-inflammation.html<br />http://www.ncbi.nlm.nih.gov/pubmed/15573908O Primitivohttp://www.blogger.com/profile/09917531397118353422noreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-76090095121424960192011-04-07T10:09:43.211-04:002011-04-07T10:09:43.211-04:00Chris, I don&#39;t want to bother you with medical...Chris, I don&#39;t want to bother you with medical questions too much, but perhaps you can give some guidance.<br /><br />I&#39;m not fat, but I do drink. 2-3 glasses of wine a day.<br /><br />I like to schedule some &quot;off-drinking&quot; time and let my liver recover. Have you seen any literature on how quickly fatty liver might resolve itself? <br /><br />Personally, when I do stop drinking, I notice subtle changes in week 1 and 2, but nothing really until month 1 or 2. Hard to measure, since sleep and hydration patters really change when you stop drinking.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-5977689274110133568.post-12228353723056853542011-04-07T04:46:46.970-04:002011-04-07T04:46:46.970-04:00Hi Chris, Have you seen this article ? Researchers...Hi Chris,<br />Have you seen this article ? Researchers find link between common dietary fat, intestinal microbes and heart disease http://goo.gl/igtFp1leonehttp://www.blogger.com/profile/18391465532808325574noreply@blogger.com