Thursday, May 31, 2012

My Interview on Dr. Lo Radio and a Quick Note on Low Triglycerides

by Chris Masterjohn

Dr. Lauren Noel was kind enough to invite me on her podcast show, Dr. Lo Radio, Tuesday evening.  You can listen to the show if you'd like here:

At 38:49, Dr. Noel asks me about female patients with triglyceride levels of 20-30 mg/dL.  I suggested hypobetalipoproteinemia.  Hypobetalipoproteinemia and abetalipoproteinemia are genetic disorders that can lead to very low triglycerides, but if they result in triglycerides below 30 mg/dL, they will generally result in total cholesterol below 100 mg/dL (1).  According to the current medical literature (1), blood lipids this low can also result from medical causes such as liver disease and hyperthyroidism, or "lifestyle" causes such as veganism and malnutrition (malnutrition could also be secondary to fat malabsorption).  If triglycerides are this low while cholesterol is normal or high, however, I would suspect that a low carbohydrate intake would be the cause.  I wouldn't be too concerned about this unless there were signs of other problems such as low thyroid function.  Dr. Noel did say that these women often have symptoms of thyroid issues, which could indicate a need to increase carbohydrate intake (or perhaps total calorie intake).  If anyone has any better insights about low triglycerides than these, please share them in the comments!

For your navigational comfort, here's a table of contents:

Saturday, May 26, 2012

My Interview With Aaron Zober of the Appropriate Omnivore

by Chris Masterjohn

Hey everyone!  I just recorded a podcast interview with Aaron Zober of the Appropriate Omnivore on a variety of topics including the lipid hypothesis, vegetarianism, Weston Price, and more.  You can check out his blog and his radio show if you like, and you can listen to our interview here (I recommend right-clicking to download it):

And here's a "table of contents" to help you navigate to the parts you're most interested in listening to:

Thursday, May 17, 2012

AJCN Publishes New PUFA Study That Should Make Us Long For the Old Days

by Chris Masterjohn

I have a new post over at Mother Nature Obeyed:

This is my response to the new study published in AJCN showing that replacing butter with sunflower oil decreases liver fat, PCSK9, and improves a handful of metabolic markers.  I begin with a critical review of the 2010 meta-analysis by Mozaffarian and colleagues claiming that the randomized, controlled trials substituting vegetable oils for saturated fats show that this swap reduces heart disease risk, which was cited by the AJCN authors in justification of their research approach.  I then move on to reviewing the animal evidence suggesting that saturated fats increase fatty liver in certain contexts while polyunsaturated fats do so in others.  I conclude by reviewing the AJCN study and lamenting its irrelevance.  I suppose this is quite long for an analysis of a study I finally conclude is irrelevant, but I hoped we might all learn a few things (especially including myself!) and perhaps score a chuckle or two in the process. 


Read more about the author, Chris Masterjohn, PhD, here.