Is there a plan to get the podcast added to Stitcher?
Hi Billy,It is already in Stitcher. I now link to the Stitcher page in the show notes for each episode.Chris
Chris, I enjoy the detailed level of biochemistry. Even when I don't follow all of it, it gives me a sense of the context and the bigger picture. It squelches the tendency to over simplify
The amount of biochemistry is great!What I enjoy most, is seeing how very smart people, can deeply analyze and research the same topic and data, yet arrive at very different conclusions! The insulin-obesity model is my favorite.. for example, Peter Attia (former President of NuSI), and Dom D'Agostino both very well credentialed, tout a low-carb ketogenic diet, and have plenty of biochemistry to show.. http://eatingacademy.com/nutrition/ketosis-advantaged-or-misunderstood-state-part-iiOn the other end, you have researchers like Stephen Guyenet who aren't so convinced:http://wholehealthsource.blogspot.com/2016/01/testing-insulin-model-response-to-dr.htmlSugar, is also a good one.. Robert Lustic (Bitter Truth fame) say fructose (and by extension HFCS) is metabolized differently than glucose, to promote weight gain. Alan Aragon makes compelling counterpoints:http://www.alanaragonblog.com/2010/02/19/a-retrospective-of-the-fructose-alarmism-debate/While the smoke settles, any plans for podcast on Intermittent fasting?
Agreed!IF may be on the list. I'll have to think about it. I'm not sure I have anything unique to add about it but if I think of something I'll share.
Does hemoglobin A1C reflect average blood glucose levels or does it not?
It is an imperfect measure of culumulative recent hyperglycemia.So, yes it does, and no it doesn't.
How can i know so much as you? What do i need to learn and study?
The best way to start is to ask more specific questions.
AWESOME episode! Would love to hear how all this relates to a1c and diabetes. I've also heard a few people talk about how a1c is not as reliable to measure average glucose as we thought and is used in clinical practice. Can we get a glycation part 2?!
Hi Tracy,Good idea! In short, it is useful but confounded by fructosamine 3-kinase activity (deglycates hemoglobin) and by red blood cell turnover (higher rate lowers Hba1c). Also, there is no evidence that Hba1c plays a causal role in diabetes.Chris
YES!!! Let's here more about that!!
Dr. Masterjohn,I'm a big fan of your work, theories and most of all your openess to discuss science from a sort of new point of view. After about a year looking for some answers to my high A1C and theorethically high average blood sugar despite a low carb diet, I finally found the answer in this podcast. I was put on a very low carb diet with the aim of reducing my A1C from 5.6 to end up at 6.1 after 6 months . I was told my average blood sugar must be in the 120 mg/dL which; was at all not possible as I was measuring my blood sugar like a freak all day long and never got any value above 110 nor stayed longer than that for more than an hour plus my FBS average was 87-90. My blood lipids were all in the healthy range, still was told I was borderline Type 2 and hypothyroid. In summary, I got worse in a very low carb diet so I did re-introduce carbs again and feel much better. I'm not and was never overweight so, not a problem at all. I will continue reading your posts as I'm still intrigued on why or what nutrient deficiencies are behind cases like mine as I've seen many people improving on a very low carb diet. It works but, it is not for every one.Thanks for sharing your work with us.Mónica
Monica, thank you for sharing your story. I've heard others like it, and it's not surprising because it has been known for over a half century that carbs increase glucose tolerance and that was the traditional rationale of standardizing carb intake for a couple weeks before a glucose tolerance test. I'm glad you're feeling better.Chris
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