Sunday, January 22, 2012

New Evidence of Synergy Between Vitamins A and D: Protection Against Autoimmune Diseases

by Chris Masterjohn

I have a new post over at Mother Nature Obeyed:


Read more about the author, Chris Masterjohn, PhD, here.

Friday, January 6, 2012

We Really Can Make Glucose From Fatty Acids After All! O Textbook, How Thy Biochemistry Hast Deceived Me!

by Chris Masterjohn

Biochemistry textbooks generally tell us that we can't turn fatty acids into glucose.  For example, on page 634 of the 2006 and 2008 editions of Biochemistry by Berg, Tymoczko, and Stryer, we find the following:
Animals Cannot Convert Fatty Acids to Glucose

It is important to note that animals are unable to effect the net synthesis of glucose from fatty acids.  Specficially, acetyl CoA cannot be converted into pyruvate or oxaloacetate in animals.

In fact this is so important that it should be written in italics and have its own bold heading!  But it's not quite right.  Making glucose from fatty acids is low-paying work.  It's not the type of alchemy that would allow us to build imperial palaces out of sugar cubes or offer hourly sweet sacrifices upon the altar of the glorious god of glucose (God forbid!).  But it can be done, and it'll help pay the bills when times are tight.