Sunday, December 30, 2012

My Interview with Dr. Mercola On Cholesterol, Vitamin K, Insulin, Blood Lipids, CT Scans, Calcification, and Heart Disease

by Chris Masterjohn, PhD

From a Christmas-celebrator to the rest of you, Merry Sixth Day of Christmas! I hope you're all enjoying whatever you might be celebrating during the season of expanding daylight and just plain enjoying life.

Dr. Mercola posted a video interview today that we had recorded a few weeks back, about cholesterol, vitamin K, insulin, blood lipids, CT scans, calcification, and heart disease. If you'd like to watch it, here it is!

Sunday, December 23, 2012

My New Article on Nutrient Synergy is Up on WestonAPrice.Org

by Chris Masterjohn, PhD

My new article from the Fall, 2012 issue of Wise Traditions, the quarterly journal of the Weston A. Price Foundation, is now up online! The article covers several examples of nutrient synergy: how methionine, B vitamins, and glycine interact to regulate methylation; how vitamins A, D and K interact to regulate growth and calcification; and how magnesium is universally important, with its regulation of calcium metabolism as an example. If you'd like to read it, you can find it here:

Friday, November 2, 2012

My AHS 2012 Talk Is Now Up! Oxidative Stress and Carbohydrate Intolerance

by Chris Masterjohn, PhD

My talk at the 2012 Ancestral Health Symposium, "Oxidative Stress and Carbohydrate Intolerance," is now freely available online! Enjoy!

Chris Masterjohn — Oxidative Stress & Carbohydrate Intolerance: An Ancestral Perspective from Ancestral Health Society on Vimeo.

Read more about the author, Chris Masterjohn, PhD, here.

Friday, October 19, 2012

Having Sex Protects Against Vitamin D Toxicity

by Chris Masterjohn, PhD

My focus for the last six years or so on the need to balance vitamin D with vitamins A and K2 has turned out to be a rather prudish solution to the soft tissue calcification that can often be caused by vitamin D. While a concoction of A and K may hold you up on the streets, the funner and more exciting solution to vitamin D toxicity lies between the sheets.

Friday, September 14, 2012

Egg Study Redux

by Chris Masterjohn, PhD

New over at Mother Nature Obeyed


In this post I correct two errors I made in my last post about this study, and further explore why it likely shows nothing more than that we accumulate plaque as we get older.

Enjoy! 

Read more about the author, Chris Masterjohn, PhD, here

Thursday, August 16, 2012

Are Egg Yolks Almost As Bad as Cigarettes At Causing the Accumulation of Arterial Plaque?

by Chris Masterjohn

New over at Mother Nature Obeyed:


Enjoy!

Read more about the author, Chris Masterjohn, hD, here.

Tuesday, July 17, 2012

I'm 95% Confident This is a Good Definition of a P Value

by Chris Masterjohn

New post over at Mother Nature Obeyed:


In this post, I explain why I consider it legitimate to read "confidence" that something is not due to chance into a P value. I discuss the differences between Bayesian and frequentist approaches, the agreement between P values derived from a significance test of the null hypothesis and those derived from the construction of a 95% confidence interval, and I use examples that include funny-looking red imps that like to steal things and lie about it.

Enjoy!

Read more about the author, Chris Masterjohn, PhD, here.

Thursday, June 21, 2012

Being Statistically Significant Is Nothing Like Being Pregnant

by Chris Masterjohn

New post over on Mother Nature Obeyed:


Enjoy!

Read more about the author, Chris Masterjohn, PhD, here.

Monday, June 4, 2012

The Maasai, an Interlude: What Does All This Sociocultural and Historical Stuff Have to Do With Heart Disease?

by Chris Masterjohn

New post over at Mother Nature Obeyed:


Enjoy!

Read more about the author, Chris Masterjohn, PhD, here.

Thursday, May 17, 2012

AJCN Publishes New PUFA Study That Should Make Us Long For the Old Days

by Chris Masterjohn

I have a new post over at Mother Nature Obeyed:


This is my response to the new study published in AJCN showing that replacing butter with sunflower oil decreases liver fat, PCSK9, and improves a handful of metabolic markers.  I begin with a critical review of the 2010 meta-analysis by Mozaffarian and colleagues claiming that the randomized, controlled trials substituting vegetable oils for saturated fats show that this swap reduces heart disease risk, which was cited by the AJCN authors in justification of their research approach.  I then move on to reviewing the animal evidence suggesting that saturated fats increase fatty liver in certain contexts while polyunsaturated fats do so in others.  I conclude by reviewing the AJCN study and lamenting its irrelevance.  I suppose this is quite long for an analysis of a study I finally conclude is irrelevant, but I hoped we might all learn a few things (especially including myself!) and perhaps score a chuckle or two in the process. 

Enjoy!

Read more about the author, Chris Masterjohn, PhD, here.

Saturday, April 7, 2012

Glutathione 101, Part 1: Cysteine Misbehaves, But Glutathione Saves

by Chris Masterjohn

New post over at Mother Nature Obeyed:


Enjoy!

Read more about the author, Chris Masterjohn, PhD, here.

Saturday, March 31, 2012

With the Wave of a Wand Raw Milk Wipes Away the Wheeze: How Our Good Friend Glutathione Protects Against Asthma

by Chris Masterjohn

New over at Mother Nature Obeyed:


Enjoy!

Read more about the author, Chris Masterjohn, PhD, here.

Sunday, January 22, 2012

New Evidence of Synergy Between Vitamins A and D: Protection Against Autoimmune Diseases

by Chris Masterjohn

I have a new post over at Mother Nature Obeyed:


Enjoy!

Read more about the author, Chris Masterjohn, PhD, here.

Friday, January 6, 2012

We Really Can Make Glucose From Fatty Acids After All! O Textbook, How Thy Biochemistry Hast Deceived Me!

by Chris Masterjohn

Biochemistry textbooks generally tell us that we can't turn fatty acids into glucose.  For example, on page 634 of the 2006 and 2008 editions of Biochemistry by Berg, Tymoczko, and Stryer, we find the following:
Animals Cannot Convert Fatty Acids to Glucose

It is important to note that animals are unable to effect the net synthesis of glucose from fatty acids.  Specficially, acetyl CoA cannot be converted into pyruvate or oxaloacetate in animals.

In fact this is so important that it should be written in italics and have its own bold heading!  But it's not quite right.  Making glucose from fatty acids is low-paying work.  It's not the type of alchemy that would allow us to build imperial palaces out of sugar cubes or offer hourly sweet sacrifices upon the altar of the glorious god of glucose (God forbid!).  But it can be done, and it'll help pay the bills when times are tight.