This past Thursday, we all showed up live on Facebook so you could ask me anything about heart disease. Here's the video, and the audio recording as a podcast.
Don't forget this Saturday at 2:00 PM eastern time you can show up live again to ask me anything about methylation! Here is the full schedule of upcoming Facebook Live events.
Listen on ITunes or Stitcher.
Click here to stream.
Right-click (control-click on the Mac) here and choose "save as" ("save link as" on Mac) to download.
Subscribe in your own reader using this RSS feed.
Read on for the shownotes.
Tonight at 8:00 PM eastern time I will be LIVE on Facebook again so you can ask me anything about heart disease. I hope to see you there!
Thank you so much for voting on the themes.
Here is the schedule for the next four events (times are all eastern time, so please make sure to adjust it to your own time zone if needed):
- Thursday, June 16, 8:00 PM eastern time: Ask Me Anything About Heart Disease
- Saturday, June 25, 2:00 PM eastern time: Ask Me Anything About Methylation Nutrients (B12, folate, choline, etc)
- Wednesday, June 29, 5:00 PM eastern time: Ask Me Anything About Vitamins A, D, and K
- Saturday, July 9, 2:00 PM eastern time: Ask Me Anything About Health, Fitness, and Nutrition (free-for-all like the first episode)
The themes are chosen but the questions aren't. Show up live, and you'll make able to ask the questions that will wind up becoming the show itself!
This past Saturday I went on Facebook Live for the first time ever so you could ask me anything about health, fitness, and nutrition. It was incredible! Thank you to everyone who came and asked questions!
Below you can watch the video or listen to the audio recording as a podcast.
Listen on ITunes or Stitcher.
Click here to stream.
Right-click (control-click on the Mac) here and choose "save as" ("save link as" on Mac) to download.
Subscribe in your own reader using this RSS feed.
Read on for the show notes.
If
you are looking for my writings on glycation and AGEs, you should start with
this article:
For a more technical and comprehensive introduction, I recommend chapter 2 of my dissertation. This is not available for free right now (your library should be able to access it, if by no other means by interlibrary loan), but I will try to make that happen in the future.
These are my podcasts about glycation:
These are my peer-reviewed articles related to AGEs:
In this episode, I wrap up glycation week by discussing why glycation
may play essential physiological roles in the body.
In the early days
of methylglyoxal research, Albert Szent-Gyorgyi, who won the 1937 Nobel
prize in Physiology or Medicine for his discovery of vitamin C and
critical steps in energy metabolism, saw the molecule as part of a
regulatory system. In the early research into glycolysis, the system
that converts methylglyoxal to pyruvate was seen as part of energy
metabolism. Only later did glycation become synonymous with toxicity.
Current science can be used to make a compelling case that methylglyoxal
is normally produced as part of glycolysis to prevent a dangerous
buildup of glyceraldehyde and that it rises during carbohydrate
restriction to help preserve much-needed glucose and to enable the
conversion of fat to additional glucose. This could be seen as an
elegant system of regulation and a key part of energy metabolism.
Nevertheless, it is unclear where the dividing line between physiology
and pathology lies, and I see the apparent rise of methylglyoxal during
carbohydrate restriction as part of a stress response that should not be
chronically activated.
Listen on ITunes or Stitcher.
Click here to stream.
Right-click (control-click on the Mac) here and choose "save as" ("save link as" on Mac) to download.
Subscribe in your own reader using this RSS feed.
Read on for the show notes.
In response to popular demand, this week is glycation week. In this
episode, I discuss the strengths and limitations of using Hba1c to
measure our cumulative recent exposure to blood glucose and diabetes
risk.
Many people will be familiar with the fact that variation in red
blood cell turnover confounds this measurement. Less well known is that
variations in the deglycating enzyme fructosamine 3-kinase (FN3K) also
confound the measurement.
Counter-intuitively, if you have a higher rate
of this deglycating enzyme but a lower rate of downstream metabolism of
3-deoxyglucosone, your lower Hba1c could actually mean MORE glycation. I
conclude that Hba1c is a useful test, but only in the context of a
bigger picture put together with more information.
Listen on ITunes or Stitcher.
Click here to stream.
Right-click (control-click on the Mac) here and choose "save as" ("save link as" on Mac) to download.
Subscribe in your own reader using this RSS feed.
Read on for the show notes.
Here is a list of all my appearances on podcasts and other online broadcasts
In this episode, I discuss some important insights from my Paleo f(x) talk and audience responses to it, including the potential dangers of treating type 1 diabetes with a low-carb diet, the importance of carbs and body fat for fertility and sex hormones, and why some people might have a great sex hormone profile on a long-term ketogenic diet despite the importance of insulin's contribution to fertility.
I also discuss Headspace meditation, contrast showers, Snapchat, U.S. Wellness Meats liverwurst, Kettle and Fire's upcoming chicken broth and chicken mushroom broth, and my interview with Ben Greenfield.
Listen on ITunes or Stitcher.
Click here to stream.
Right-click (control-click on the Mac) here and choose "save as" ("save link as" on Mac) to download.
Subscribe in your own reader using this RSS feed.
Read on for the show notes and relevant links.
No, I don't mean that ironically. A little hyperbolic? A little, but not ironic.
This
is my new Examine.Com Research Digest Editorial about some
underappreciated benefits of glucose and insulin. The Research Digest
costs money, but as a member of my audience you can read my editorial
and also get a sneak peak at the issue for free. Check it out!
